Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides

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Keyword

Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides

Sukurta: 31 January 2024
Kryptis: Biotechnologijos

This invention teaches a class of fluorinated benzensulfonamides of general structure I, as shown:

which are useful for inhibiting protein amyloid aggregation. The compounds taught can be used in pharmaceutical compositions in effective amounts to treat illnesses that result from protein amyloid aggregation.

Inventors: Daumantas Matulis; Andrius Sakalauskas; Virginija Dudutienė; Mantas Žvirblis; Mantas Žiaunys; Vytautas Smirnovas

Jurisdiction: US, EP

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