Patents

Vilnius University researchers have been the authors of many international patents (Europe, USA, Japan and other). Inventions developed at the university are interdisciplinary so the title and descriptive keywords of the invention, patents and/or patent applications may include several research and technology fields. May you consider licensing opportunities of Vilnius university patents or patent applications, contact the Innovation Office of Science and Innovation Department (.).

Keyword

Hydrolases and uses thereof

Sukurta: 04 February 2025
Kryptis: Biochemija

The present invention is provided hydrolases originating from prokaryotic, archaea and eukaryotic cells, capable of regioselectively converting N4-acylcytidine, N4-alkylcytidine, N4-carboxycytidine, S4-alkylthiouridine and O4-alkoxyuridine derivatives to uridine derivatives. The present disclosure provides using these polypeptides in the processes: 1) for making chemical uridine derivatives from N4-acylcytidines, N4-alkylcytidines, N4-carboxycytidine, S4-alkylthiouridines and O4-alkoxyuridine compounds; 2) for making pyrimidine compounds such as intermediates in the production active pharmaceutical drugs; 3) for the prodrug activation; 4) in combination with N4-acylcytidines, N4-alkylcytidines, S4-alkylthiouridines and O4-alkoxyuridines for the selection of enzymes.

Inventors: Rolandas Meškys, Nina Urbelienė, Daiva Tauraitė, Matas Tiškus, Viktorija Preitakaitė

Jurisdiction: EP, LT

Link to espacenet