Antibodies for photoactive protein manipulation
Sukurta: 23 rugpjūčio 2023
- Kryptis: Biotechnologijos
The invention describes a high affinity monoclonal antibody 12B6 that specifically interacts with a photolabile DMNB moiety. This antibody is suitable for recognizing DMNB groups in proteins (and potentially other biomolecules). The interaction of the antibody and the unique DMNB group allows the manipulation of proteins labeled with photolabile groups by immunoprecipitation.
Inventors: Saulius Klimašauskas; Rasa Rakauskaitė; Giedrė Urbanavičiūtė; Rita Lasickienė, Martynas Simanavičius; Aurelija Žvirblienė
Jurisdiction: LT, EP