Faculty of Chemistry

Sukurta: 27 August 2013

chf 24 Naugarduko, LT-03225 Vilnius
Tel. 233 0987, fax 233 0987
E-mail:
www http://www.chf.vu.lt

Dean – Prof. Habil. Dr. Aivaras Kareiva

STAFF

46 teachers (15 habilitated doctors and 32 doctors), 13 research fellows (2 habilitated doctors and 14 doctors), 46 doctoral students.

Department of Analytical and Environmental Chemistry
Department of General and Inorganic Chemistry
Department of Physical Chemistry
Department of Organic Chemistry
Department of Polymer Chemistry

MAIN RESEARCH AREAS OF THE FACULTY

Synthesis and investigation of novel materials and nanostructures, development of analysis methods:
Electrochemical processes at the interphase
Creation of analytical methods and instruments for analysis of environmental and industrial objects
New materials, nano-structures and surfaces: synthesis, characterization, technologies.

DOCTORAL DISSERTATIONS MAINTAINED IN 2012

J. Bagdzevičienė. Investigation and description of ancient pigments in paintings and archaeological glass finds.

A. Orentienė. Investigation of chromatographic behaviour of imidazolium ionic liquid cations by ultra performance liquid chromatography techniques.

E. Panaščikaitė. Determination of manganese and chromium by electroanalytical stripping methods research.

A. Prichodko. Microextraction and gas chromatographic determination of parabens.

I. Stankevičienė. Synthesis and coatings production of carbonaceous nanostructures.

A. Gatelytė. Synthesis and characterization of novel black pigments.

K. Klemkaitė-Ramanauskė. Synthesis, modification and characterization of Mg/Al, Co/Mg/Al and Ni/Mg/Al layered double hydroxides.

A. Katelnikovas. Synthesis and characterization of luminescent materials for solid state ligot sources.

T. Maliar. Synthesis of iron particles in aqueous and oil media and application in trybosystems.

J. Dodonova. Synthesis and photophysical properties of pyrrolo[3,2-d]pyrimidine-core based oligoarylenes.

R. Bukšnaitienė. Study on cyclization reactions of heterocyclic compounds bearing ethynyl and formyl groups in close proximity to each other.

E. Čapkauskaitė. Synthesis of carbonic anhydrase inhibitors and analysis of their structure - activity relationship.

G. Bagdžiūnas. Synthesis, structural and association studies of chiral supramolecular polycyclic tectones based on bicyclo[3.3.1]nonane framework.

CONFERENCES AND SEMINARS ORGANIZED IN 2012

14th iInternational cConference-sSchool Advanced Materials and Technologies

International cConference Nanochemistry and Nanomaterials

DEPARTMENT OF ANALYTICAL AND ENVIRONMENTAL CHEMISTRY

24 Naugarduko , LT-03225 Vilnius
Tel. 233 7517, 219 3114, fax 233 0987
E-mail:

Head - Prof. Dr. Stasys Tautkus

STAFF

Professors: Habil. Dr. S. Armalis, Habil. Dr. A.Padarauskas, Dr. S. Tautkus, Dr. V. Vičkačkaitė.
Docent: Dr. A. Ramanavičienė.
Lecturers: Dr. A. Kaušaitė-Minkštimienė, Dr. J. Kiuberis, Dr. V. Olšauskaitė.
Research fellows: Dr. J. Kiuberis (part-time), Dr. V. Vičkačkaitė (part-time).
Doctoral students: J. Baniukevič, J. Bagdzevičienė, N. Karlonas, J. Kirlytė, A. Linkevičiūtė, V. Mažeiko, V. Šmitienė, A. Orentienė, E. Panaščikaitė, A. Prichodko, I. Razmislevičienė, A. Stirkė, J. Voronovič.

RESEARCH INTERESTS

Investigation of new HPLC and capillary electroforetic systems
Development of stripping analysis techniques
Investigation of gas chromatographic analysis
Bio-, Immuno-, DNA- sensors based on nanostructured conducting polymers
Determination of trace elements using atomic absorption spectrometric, spectrophotometric and kinetic methods

RESEARCH PROJECTS CARRIED OUT IN 2012

Projects Supported by University Budget

Chromatographic and Electromigrative Techniques: Development and Application of New Preconcentration and Separation Systems. Prof. A. Padarauskas. 2011–2015.

A reliable, sensitive and rapid method for determination of nicotine and three minor alkaloids (cotinine, anabasine and nornicotine) in tobacco by ultra-high performance liquid chromatography in hydrophilic interaction chromatography mode coupled with tandem mass spectrometry has been established. The performance of the proposed method was tested for the extraction and determination of the four alkaloids in cigarette tobacco and satisfactory results were achieved.
Ultra performance liquid chromatography equipped with a photodiode array dedector was employed for the identification of main constituents of natural dyes. The dyestuffs investigated were the following: luteolin, apigenin, quercetin, rutin, gallic acid, carminic acid, alizarin, purpurin and indigotin. The method was applied for the identification of dye compounds in historical textiles samples.
Gas chromatographic-mass spectrometric method for the identification and determination of organotin compounds in aqueous solutions has been employed. Prior to the analysis organotin compounds were derivatized using sodium tetraethylborate as derivatization reagent. For the extraction of derivatized organotin compounds, hollow fiber liquid phase microextraction method has been suggested and the extraction conditions have been optimized.

Investigation of Instrumental Methods of Analysis of Environmental, Industrial, Biological and Cultural Heritage Objects. Prof. S. Tautkus. 2011–2015.

Nanotechnology has recently become one of the most exciting forefront fields offering technological advantages suitable for analytical chemistry. In some cases a combination of nanomaterials and nanotechnological approches resolves challenging bioanalytical problems, including specificity, stability and sensitivity.
Different glucose biosensors based on glucose oxidase immobilised on bare carbon rod electrode modified with gold nanoparticles (Au-NPs) of 3.5 nm, 6 nm and 13 nm were investigated. Enzymatic polymerisation of pyrrole was applied to increase linear detection range of biosensors. The influence of the formed polypyrrole layer on sensitivity and Michaelis-Menten kinetics of designed electrochemical biosensors was investigated, The linear glucose detection interval depends on the duration of polymerisation. The sensitivity of analytical systems modified with polypyrrole depended on the sizes of Au-NPs. Smaller Au-NPs based systems exhibited higher amperometric responses at the same concentration of glucose before and after the formation of polypyrrole layer.
Number of immunosensors based on different antigen and antibody interaction registration techniques such as surface plasmon resonance, quartz microbalance, X-ray photoelectron spectroscopy, electrochemical technique, atomic force microscopy, total internal reflection ellipsometry and some others ewre used for registration of antigen and antibody interaction. Another very promising technique is surface-enhanced Raman scattering (SERS), which can detect picomoles to femtomoles of analyte in the samples. This phenomenon provides a highly specific and sensitive strategy for molecular identification and promotes the wide developments of SERS-based sensors using noble metal nanoparticles (e.g., Ag, Au and Pt). In our study magnetic gold nanoparticle (MNP-Au) and gold nanorods (Au-NRs) were used in SERS-based sandwich immunoaasay for bovine leukemia virus antigen detection.The native and fragmented specific antibodies were immobilized on MNP-Au. The antibody immobilization and antigen capturing efficiency were recorded by high performance liquid applied for the enhancement of analytical signal after immune complex with analyte formation on MNP-Au. The sensitiviti of the developed assay was investigated and compared.
The aim-to investigate of Kernavės- Kriveikiškių blue, brown and glass beads (XIII-XIV th century) using SEM, FTIR spectroscopy, EDX and ICP-MS analysis. Continuing the work we have chosen less frequently found in the red, blue and brown archaeological glass beads (XIII-XIV century). The materials used in the manufacture of glass are divided into four groups: the main component of glass – SiO2, compounds, which giving the glass colors, flux, which decreases the melting temperature of the mixture, modifiers, which are added to the melted materials to improve their properties.
EDX and ICP-MS methods showed that all three main components in glass beads are SiO2,
clarification – MnO, fluxes – Na2CO3 , PbO and K2CO3 and modifiers of Al2O3. EDX and ICP-MS methods showed that the blue colour for the samples No.1 and No.2 are giving Co2+ and Fe3+ ions, for the sample No.3 – Ag+ ions, the brown colour for the sample No.4 – Fe2+/Fe3+ ions, the red colour for the sample No.5 – Cu2+ ions. OM and SEM bead core cross-sectional images showed that the blue samples No.1 and No.2 are damaged by erosion around the bead volume, in the sample blue No.3 is visible only superficial erosion, and the brown and red samples No.4 and No.5 are only slightly damaged. FTIR spectroscopy confirmed that the beads have been affected by external and internal erosion, down -P-O-H and –C=O functional groups include the erosion products that are the result of archaeological environment.
A method for the determination of lead in mushrooms by flame atomic absorption spectro- metry has been suggested. The calibration graph for lead was linear in the range of 0.25–4.0 µg/ml. The effects of various parameters such as air and gas pressure, the influence of nitric acid concentration, the effect of time on the absorbance of lead have been studied. The selectivity of the determination of lead also was studied. The limiting interfering Pb/M ratious (the determination error±10%) have been determined. According to the interfering effect examined metals are ordered as: Li>Cr, Mn, Mg, Al>Ca>Fe>K, Co, Ni, Cu, Zn, Cd, Ba, Na, Bi and Sr.
The proposed procedure was applied to the determination of lead in 3 species of edible mushrooms. The relative standart deviation (n=5) was in the range from 1.2 to 3.7%. The recovery was found to be ranged between 95 and 99%.

Projects, Programmes, Issues Supported by the Research Council of Lithuania

Application of Micromembrane Devices for the Registration of Specifie Antigen-Antibody Interaction (No. MIP-059/2012). Doc. A. Ramanavičienė 2013–2015.

Lithuania-Belarus bilateral cooperation in science and technology program, project Application of Redox Enzymes in New Biofuel Cells (No. TAP LB 17/2012. Doc. A. Ramanavičienė 2012–2013.

MAIN PUBLICATIONS

Articles

T. Petrėnas, J. Kiuberis, O. Opuchovič, S. Tautkus, A. Kareiva. A closer look at the ancient bricks of historical monuments: Essential step for the conservation of pottery // Chemija / Lietuvos mokslų akademija. Vilnius : Lietuvos mokslų akademijos leidykla. 2012, t. 23, nr. 3, p. 194-202.

M. Stoica, L. Mikoliūnaitė, A. Ramanavičienė, P. Alexe, G. Carac, R. Dinica, J. Voronovič, A. Ramanavičius. Corrosion study of stainless steel incubated in solutions consisting of biocide (Oxonia-ActiveĀ®) and Aspergillus niger suspension // Chemija / Lietuvos mokslų akademija. Vilnius : Lietuvos mokslų akademijos leidykla. 2012, t. 23, nr. 3, p. 180-186.

L. Taujenis, V. Olšauskaitė. Identification of main constituents of historical textile dyes by ultra performance liquid chromatography with photodiode array detection // Chemija / Lietuvos mokslų akademija. Vilnius : Lietuvos mokslų akademijos leidykla. 2012, t. 23, nr. 3, p. 210-215.

N. Karlonas, A. Padarauskas, A. Ramanavičius, Z. Minkuvienė, A. Ramanavičienė. Rapid and highly sensitive determination of clonazepam and 7-aminoclonazepam in whole blood using gas chromatography with negative-ion chemical ionization mass spectrometry // Chemija / Lietuvos mokslų akademija. Vilnius : Lietuvos mokslų akademijos leidykla. 2012, t. 23, nr. 2, p. 91-99.

N. German, S. Armalis. Voltammetric determination of naphthalene, fluorene and anthracene using mixed water-organic solvent media // Chemija / Lietuvos mokslų akademija. Vilnius : Lietuvos mokslų akademijos leidykla. 2012, t. 23, nr. 2, p. 86-90.

S. Raugelė, S. Tautkus, A. Kareiva, V. Sirvydis. Impact on porcine heart valve tissue treating with carbodiimide // Seminars in cardiovascular medicine. Vilnius : Lietuvos širdies asociacija. 2012, vol. 15, no. 6, p. [1-3].

A. Ramanavičienė, N. German, A. Kaušaitė-Minkštimienė, J. Voronovič, J. Kirlytė, A. Ramanavičius. Comparative study of surface plasmon resonance, electrochemical and electroassisted chemiluminescence methods based immunosensor for the determination of antibodies against human growth hormone // Biosensors & bioelectronics. Oxford : Elsevier Advanced Technology. 2012, vol. 36, iss. 1, p. 48-55.

J. Baniukevič, J. Kirlytė, A. Ramanavičius, A. Ramanavičienė. Comparison of oriented and random antibody immobilization techniques on the efficiency of immunosensor // Procedia engineering. Amsterdam : Elsevier BV. 2012, vol. 47, p. 837-840.

A. Ramanavičius, Y. Oztekin, Z. Balevičius, A. Kaušaitė-Minkštimienė, V. Krikštolaitytė, I. Balevičiūtė, V. Ratautaitė, A. Ramanavičienė. Conducting and electrochemically generated polymers in sensor design (mini review) // Procedia engineering. Amsterdam : Elsevier BV. 2012, vol. 47, p. 825-828.

Y. Oztekin, M. Tok, E. Bilici, L. Mikoliūnaitė, Z. Yazicigil, A. Ramanavičienė, A. Ramanavičius. Copper nanoparticle modified carbon electrode for determination of dopamine // Electrochimica acta. Oxford : Pergamon-Elsevier Ltd. 2012, Vol. 76, p. 201-207.

A. Ramanavičius, N. Ryškevič, A. Kaušaitė-Minkštimienė, U. Samukaitė-Bubnienė, I. Balevičiūtė, Y. Oztekin, A. Ramanavičienė. Fluorescence study of glucose oxidase self-encapsulated within polypyrrole // Sensors and actuators B: Chemical. Amsterdam : Elsevier BV. 2012, vol 171-172, p. 753-759.

N. German, A. Ramanavičius, J. Voronovič, A. Ramanavičienė. Glucose biosensor based on glucose oxidase and gold nanoparticles of different sizes covered by polypyrrole layer // Colloids and surfaces A: physicochemical and engineering aspects. Amsterdam : Elsevier BV. 2012, vol. 142, no 5, p. 224-230.

N. German, J. Voronovič, A. Ramanavičius, A. Ramanavičienė. Gold nanoparticles and polypyrrole for glucose biosensor design // Procedia engineering. Amsterdam : Elsevier BV. 2012, vol. 47, p. 482-485.

V. Vičkačkaitė, A. Padarauskas. Ionic liquids in microextraction techniques // Central European journal of chemistry. Warsaw : Versita, co-published with Springer-Verlag GmbH. 2012, vol. 10, no. 3, p. 652-674.

Y. Oztekin, Z. Yazicigil, A. Solak, Z. Uztundac, A. Okumus, Z. Kilic, A. Ramanavičienė, A. Ramanavičius. Phenanthroline derivatives electrochemically grafted to glassy carbon for Cu(II) ion detection // Sensors and actuators B. Chemical. Lausanne : Elsevier Science. 2012, vol. 166-167, p. 117-127.

B. Abakevičienė, A. Žalga, S. Tautkus, J. Pilipavičius, E. Navickas, A. Kareiva, S. Tamulevičius. Synthesis of YSZ thin films by the novel aqueous sol-gel citrate-precursor method // Solid state ionics. Amsterdam : Elsevier Science BV. 2012, Vol. 225 : Proceedings of the 18th International Conference on Solid State Ionics Warsaw, Poland, July 3 -8, 2011. p. 73-76.

A. Žarkov, A. Žalga, S. Tautkus, A. Kareiva. Novel analytical approach for the determination // Latvian Journal of Chemistry. Salaspils : Institute of Inorganic Chemistry of the Riga Technical University. 2012, no. 4, p. 428-435.

COOPERATION

Institute of Chemistry (Lithuania)
Institute of Biochemistry (Lithuania)
Institute of Physics (Lithuania)
CC Fermentas, part of Thermo Fisher Scientific (Lithuania)
Namuir University (Belgium)

OTHER SCIENTIFIC ACTIVITIES

Prof. A. Padarauskas –

editorial board member of the journal Chemija (Chemistry).

Doc. A. Ramanavičienė –

expert of international and national programs: FP7-PEOPLE-IIF-IEF-IOF-2012; Research Council of Lithuania – 2012.

DEPARTMENT OF GENERAL AND INORGANIC CHEMISTRY

24 Naugarduko, LT-03225 Vilnius
Tel. 219 3110, fax 233 0987
E-mail:

Head – Prof. Habil. Dr. Aivaras Kareiva

STAFF

Professors: Habil. Dr. A. Abrutis, Habil. Dr. J. Barkauskas, Habil. Dr. A. Beganskienė, Habil. Dr. V. Daujotis, Habil. Dr. R. Juškėnas (part-time), Habil. Dr. A. Kareiva, Dr. R. Raudonis, Dr. A. Selskis (part-time), Dr. J. Senvaitienė (part-time).
Docents: Dr. E. Garškaitė, Dr. D. Jasaitis, Dr. V. Kubilius, Dr. V. Plaušinaitienė, Dr. A. Žalga.
Lecturer: Dr. I. Grigoravičiūtė-Puronienė (part-time).
Research fellows: Habil. Dr. A. Abrutis (part-time), Dr. I. Bogdanovičienė, Dr. I. Grigoravičiūtė, Dr. V. Kubilius (part-time), Dr. V. Plaušinaitienė (part-time), Dr. Z. Šaltytė.
Doctoral students: K. Klemkaitė, I. Stankevičienė, A. Katelnikovas, A. Stanulis, A. Jankevičiūtė, T. Petrėnas, R. Skaudžius, J. Trinkunaite Felsen, O. Darčanova, J. Pilipavičius, E. Kielė.

RESEARCH INTERESTS

Chemistry of volatile metal-organic precursors
Dielectric, ferroelectric and piezoelectric materials
High-temperature superconductors for various applications
Magnetic and magnetoresistant materials
Materials with photocatalytic activity
Transparent conducting oxides (TCO)
Multilayered functional heterostructures and superlattices
Metal-organic chemical vapour deposition (MOCVD) of functional oxide layers and multilayers
Developments of aerosol-pyrolysis technique for oxide films
Conservation of cultural heritage
Synthesis and characterization of graphene and other nano-structured carbonaceous materials
Synthesis of graphene membranes
Synthesis and applications of silica nano-particles
Synthesis and characterization of inorganic-organic hybrid materials
Sol-gel synthesis and investigations of advanced nano-materials (bioceramic, optical materials, superconductors)
Film and powder synthesis by wet chemistry methods
Nanostructural materials
Surfaces and interfaces
Synthesis and characterization of different molybdates and tungstates
Development of dual-piezoelectric resonator technique for interfacial liquid viscosity and density measurements

RESEARCH PROJECTS CARRIED OUT IN 2012

Projects Supported by University Budget

Synthesis of Functional Oxide Films and Heteroepitaxial Structures by MOCVD (Metalorganic Chemical Vapour Deposition). Prof. A. Abrutis. 2011–2020.

Synthesis and Characterization of Polycrystalline and Amorphous Materials. Prof. A. Kareiva and Prof. J. Barkauskas. 2011–2020.

Electrochemical Adsorption. Prof. V. Daujotis. 2011–2015.

Synthesis of graphite oxide using different oxidizing agents. Preparation of graphite oxide membranes on polymer, glass and metal substrates. Preparation of graphene membranes on polymer, glass and metal substrates. Examination of graphite oxide and graphene membranes. Transfer of graphene membranes and coatings. TiO2 nanofilms were deposited by chemical bath deposition method. The influence of solution chemistry on the microstructure of films has been investigated. Zeta potential measurements while varying composition of the solution were performed and a stability of the solution has been evaluated. Furthermore, the influence of the deposition time and metal ion concentration in the solution on the film thickness was also examined. Moreover, the contact angle measurements were performed. Results have shown that wettability of thin films is strongly influenced by the surface morphological properties.
Solvatochromatic properties of fluorenone-based compounds were investigated. The influence of structural changes of molecule on the absorption and emission features was examined, and the effect of solvent polarity on the compound fluorescence intensity has been studied. Results showed that introducing electron donating or withdrawing group into a molecule the stabilization of the electron density of the system can be achieved.
Morphological and structural features of deposited Cu-In-S compounds were investigated. Their physicochemical properties were monitored by introducing various amount of the dopand (Zn, Ni and Sb) in the crystal lattice. A homogeneous distribution of chemical elements has been revealed and electrochemical performance of produced films was evaluated. The results showed that material when Zn is introduced as a dopant hives the best photocatalitic response and that was associated with defects present in the crystal lattice.
The calcination and systematic characterization of hydroxyapaptite (HA) precursor and sintered powders were performed. Materials were calcined using different annealing regimes. The influence of time annealing regime on the crystallinity of material was analyzed. Furthermore, the relationship between calcination time and the carbonate amount present in the HA lattice was evaluated. Results showed that increasing annealing time the carbonate amount diminishes.
The synthesis of Al2(MoxW1-xO4)3 compounds doped with Eu2O3 using both aqueous sol-gel technique and liquid state plasma method was successfully performed. The crystal structure and surface morphology of obtained materials were also investigated by XRD and SEM techniques. The elemental analysis and particle size distribution measurements showed that liquid state plasma method is a good tool in order to obtain micro-sized spherical particles. Besides, sol-gel technique was successfully applied for the preparation of La-Mo-Eu-O tartrate gel precursors using different starting compounds. The optical properties of synthesized gels with initial composition of La2Mo3O12:xEu3+ by UV-Vis spectroscopy were investigated. The results let us to conclude, that the origin of starting materials significantly influences the reflectance of final europium doped ceramic compounds. Moreover, the efforts to obtain of both Ga2Mo3O12 and Ga2W3O12 oxides also were made. In despite, no positive evidences of crystal phases of desirable compounds were achieved. Finally, the thermal behaviour of ZnMoxW1-xO4 citrate and tartrate gels by TG/DSC analysis were investigated.
YAG powders substituted by samarium were prepared by simple an aqueous sol-gel method. It was demonstrated, however, that the total substitution of yttrium by samarium does not proceed in the YAG. Pure cubic garnet phase was formed only at low concentration of samarium. Different aqueous sol-gel chemistry routes based on phosphoric acid or ammonium–hydrogen phosphate as the phosphorus precursors, calcium acetate monohydrate as source of calcium ions have been used to prepare calcium hydroxyapatite (HAp). A single-walled carbon nanotubes and silica (SWNTs/Silica) composite coatings were prepared by sol-gel method using spin-coating technique. Methyl–modified silica coatings were structured on the surface of copper and steel.
Various functional oxide layers have been MOCVD grown and investigated: high-k dielectric, high temperature superconductors, photocatalytic, magnetoresistant layers, and multilayered structures. Technological developments of MOCVD and Aerosol-pyrolysis techniques were carried out.
High-frequency admittance analysis of quartz resonator in contact with aqueous solution of sodium hexafluorophosphate has shown that adsorption of this anion can be neglected and the potential dependent changes of resonant frequencies of dual-piezoelectric resonator can be assigned to the changes of interfacial water viscosity and density with potential. When piezoelectric resonator measurements are performed in the solutions of more strongly adsorbing anions, the changes of resonant frequencies changes with potential can also be used to estimate interfacial water viscosity. However, the effects of anion adsorption must be first evaluated and taken into account when calculating water viscosity from frequency changes.

Projects, Programmes, Issues Supported by Lithuanian Council of Science

MOCVD Synthesis of Piezoelectric Films for Applications in Sensors Based on Surface Acoustic Waves. National Grant from the Research Council of Lithuania. Contract Nr. MIP-69/2011. Prof. A.Abrutis. 2011–2012.

Sol-Gel Synthesis and Characterization of New Nano-Optical Materials. National Grant from the Research Council of Lithuania for Posdoctoral studies. (SF-PD-2010-08-10-0228) Prof. A. Kareiva. 2011–2012.

Synthesis and Characterization of Nanoscaled Materials for Biotechnological and Optical Applications. Taiwan-Latvia-Lithuania Cooperation Project. Contract No. TAP-04/2011. Prof. A. Kareiva. 2011–2013.

PI-MOCVD Synthesis of (K,Li)(Nb/Ta)O3 Films and Applications for Sensors Based on Surface Acoustic Waves. Lithuania-France scientific collaboration programme “Gilliber” project Grant from the Research Council of Lithuania. Contract Nr. TAP-11/2011. Prof. A.Abrutis. 2011–2012.

Sol-Gel Synthesis, Characterization and Application in Odontology and Orthopedics of Calcium Nanophosphates. National Grant from the Research Council of Lithuania for Posdoctoral studies. (SF-PD-2012-01-16-0294) Prof. A. Kareiva. 2012–2013.

Design of New Sol-Gel Materials for Biotechnological Applications. Lithuania-UKRAINE Cooperation Project. Prof. A. Kareiva. 2012–2013.

Technological Processes of Membranes Production for Micro-Solid Oxide Fuel Cells (MIKROKOKE-2). National Grant from Research Council of Lithuania. Prof. A. Kareiva. 2012–-2014.

MAIN PUBLICATIONS

Articles

J. Trinkūnaitė-Felsen, A. Žalga, A. Kareiva. Characterization of naturally derived calcium compounds used in food industry // Chemija / Lietuvos mokslų akademija. Vilnius : Lietuvos mokslų akademijos leidykla. 2012, t. 23, nr. 2, p. 76-85.

B. Rakovska, A. Valiūnienė, A. Malinauskas, V. Kubilius, R. Valiūnas. Electrochemical formation of polyaniline on Ti and electrochemically oxidized Ti electrodes // Chemija / Lietuvos mokslų akademija. Vilnius : Lietuvos mokslų akademijos leidykla. 2012, t. 23, nr. 1, p. 12-17.

J. Blažytė, A. Beganskienė. Nevandeninių popieriaus šarminimo metodų paieška ir tyrimas // Lietuvos Dailės muziejaus metraštis. 2010, t. 14, p. 254-280. [vėluojanti].

M. Liubinienė, A. Beganskienė, J. Petrauskienė, J. Lukšėnienė. Paviršinio aktyvumo medžiagų panaudojimo galimybės dokumentų ir grafikos kūrinių konservavime // Lietuvos Dailės muziejaus metraštis. 2010, t. 14, p. 281-295.

S. Šakirzanovas, A. Katelnikovas, D. Dutczak, A. Kareiva, T. Justel. Concentration influence on temperature-dependent luminescence properties of samarium substituted strontium tetraborate // Journal of Luminescence. Amsterdam : Elsevier BV. 2012, vol. 132, no. 1, p. 141-146.

R. Trusovas, G. Račiukaitis, J. Barkauskas, R. Mažeikienė. Laser Induced Graphite Oxide/Graphene Transformation // Journal of Laser Micro / Nanoengineering. Osaka : Japan Laser Processing Society. 2012, Vol. 7, no. 1, p. 49-53.

J. Barkauskas, J. Dakševič, R. Juškėnas, R. Mažeikienė, G. Niaura, G. Račiukaitis, A. Selskis, I. Stankevičienė, R. Trusovas. Nanocomposite films and coatings produced by interaction between graphite oxide and Congo red // Journal of materials science. New York : Springer. 2012, Vol. 47, no. 15, p. 5852-5860.

N. Dubnikova, E. Garškaitė, R. Raudonis, A. Kareiva. Neodymium substitution effects in sol-gel derived Y3ā�’xNdxAl5O12 // Materials chemistry and physics. Lausanne : Elsevier S.A. 2012, vol. 137, no. 2, p. 660-664.

R. Skaudžius, J. Pinkas, R. Raudonis, A. Selskis, R. Juškėnas, A. Kareiva. On the limitary radius of garnet structure compounds Y3Al5 xMxO12 (M Ā¼ Cr, Co, Mn, Ni, Cu) and Y3Fe5 xCoxO12 (0 x 2.75) synthesized by solegel method // Materials chemistry and physics. Lausanne : Elsevier S.A. 2012, vol. 135, no. 2-3, p. 479-485.

A. Bertašytė, V. Plaušinaitienė, A. Abrutis, T. Murauskas, P. Boulet, S. Margureon, J. Gleize, S. Robert, V. Kubilius, Z. Šaltytė. Residual stresses and clamped thermal expansion in LiNbO3 and LiTaO3 thin films // Applied physics letters. Melville: American Institute of Physics. 2012, vol. 101, iss. 12, Art. no. 122902(5 p.).

A. Jankevičiūtė, Z. Karoly, N. Tarakina, J. Szepvolgyi, A. Kareiva. Synthesis and characterization of spherical amorphous alumo-silicate nanoparticles using RF thermal plasma method // Journal of non-crystalline solids. Amsterdam : Elsevier BV * North-Holland. 2012, Vol. 359, p. 9-14.

A. Katelnikovas, J. Plewa, D. Dutczak, S. Moller, D. Enseling, H. Winkler, A. Kareiva. Synthesis and optical properties of green emitting garnet phosphors for phosphor-converted light emitting diodes // Optical materials. Amsterdam, Elsevier Science BV. 2012, vol. 34, iss. 7, p. 1195-1201.

A. Katelnikovas, J. Plewa, S. Šakirzanovas, D. Dutczak, D. Enseling, F. Baur, H. Winkler, A. Kareiva, T. Justel. Synthesis and optical properties of Li3Ba2La3(MoO4)8:Eu3+ powders and ceramics for pcLEDs // Journal of Materials Chemistry. Cambridge : Royal Society of Chemistry. 2012, Vol. 22, iss. 41, p. 22126-22134.

A. Stanulis, A. Hardy, D. De, J. D'Haen, B. Van, A. Kareiva. SnO2 thin films from an aqueous citrato peroxo Sn(IV) precursor // Journal of sol-gel science and technology. New York : Springer New York LLC. 2012, vol. 62, no. 1, p. 57-64.

A. Stanulis, S. Šakirzanovas, B. Van, A. Kareiva. Sol-gel (combustion) synthesis and characterization of different alkaline earth metal (Ca, Sr, Ba) stannates // Journal of sol-gel science and technology. New York : Springer New York LLC. 2012, vol. 64, no. 3, p. 643-652.

M. Misevičius, O. Ščit, I. Grigoravičiūtė-Puronienė, G. Degutis, I. Bogdanovičienė, A. Kareiva. Sol-gel synthesis and investigation of un-doped and Ce-doped strontium aluminates // Ceramics International. Oxford : Pergamon - Elsevier. 2012, vol. 38, iss. 7, p. 5915-5924.

D. Jonynaitė, D. Jasaitis, R. Raudonis, A. Selskis, R. Juškėnas, J. Senvaitienė, A. Kareiva. Sol-gel synthesis and study of neodymium substitution effects in Co-Al-Nd-O system with possible applications as novel inorganic pigments // Central European Journal of Chemistry. Warsaw : Versita, co-published with Springer-Verlag GmbH. 2012, Vol. 10, no. 5, p. 1574-1593.

E. Garškaitė, G. Pan, T. Yang, S. Huang, A. Kareiva. The study of preparation and photoelectrical properties of chemical bath deposited Zn, Sb and Ni-doped CuInS2 films for hydrogen production // Solar energy. Oxford : Elsevier Ltd. 2012, vol. 86, no. 9, p. 2584-2591.

K. Tonsuaadu, A. Žalga, A. Beganskienė, A. Kareiva. Thermoanalytical study of the YSZ precursors prepared by aqueous sol-gel synthesis route // Journal of thermal analysis and calorimetry. Budapest : Akademiai Kiado Rt. 2012, vol. 110, no 1, p. 77-83.

O. Ščit, E. Garškaitė, A. Kareiva. Samarium-substitution effects in sol-gel derived yttrium aluminium garnet // Proceedings of the international conference nanomaterials: applications and properties. Sumy : Sumy State University Publishing. 2012, vol. 1, no 1, p. art. no 01PCN14 (3 p.).

M. Mackevičius, F. Ivanauskas, A. Kareiva, D. Jasaitis. A closer look at the computer modeling and sintering optimization in the preparation of YAG // Journal of mathematical chemistry. Dordrecht : Springer Netherlands. 2012, Vol. 50, no. 8, p. 2291-2302.

C. Baristiran-Kaynak, M. Lukosius, B. Tillack, C. Wenger, A. Abrutis, M. Skapas. CexAlyOz/TiN stack analysis for Metal-Insulator-Metal applications: Effect of annealing and the metal electrode deposition method // Thin solid films. Lausanne : Elsevier Science. 2012, vol. 520, no. 14, p. 4518-4522.

R. Fallica, F. Volpe, M. Longo, C. Wiemer, O. Salicio, A. Abrutis. Electronic properties of crystalline Ge1-xSbxTey thin films // Applied physics letters. Melville: American Institute of Physics. 2012, vol. 101, iss. 10, Art. no. 102105(4 p.).

S. Balevičius, N. Žurauskienė, V. Stankevič, S. Keršulis, V. Plaušinaitienė, A. Abrutis, S. Zherlitsyn, T. Herrmannsdorfer, J. Wosnitza, F. Wolff-Fabris. Nanostructured thin manganite films in megagauss magnetic field // Applied physics letters. Melville: American Institute of Physics. 2012, vol. 101, iss. 9, Art. no. 092407(4 p.).

Materials of conferences

E. Borovikovaitė, J. Pilipavičius, R. Raudonis, A. Beganskienė, A. Kareiva. Design and characterization of silica coatings on glass substrate // Chemistry and chemical technology of inorganic materials : proceedings of scientific conferenceChemistry and chemical technology. Kaunas : Technologija, 2012, p. 54-58.

M. Liubinienė, A. Beganskienė, I. Bubinienė, A. Kareiva. Fungicidal effects of materials on paper and paper with gall inks // Chemistry and chemical technology of inorganic materials : proceedings of scientific conferenceChemistry and chemical technology. Kaunas : Technologija, 2012, p. 177-182.

O. Darčanova, T. Sabirovas, A. Beganskienė, A. Kareiva. Impact of antioxidant on stability of paper with metal gall inks // Chemistry and chemical technology of inorganic materials : proceedings of scientific conferenceChemistry and chemical technology. Kaunas : Technologija, 2012, p. 183-186.

O. Opuchovič, T. Petrėnas, A. Kareiva. Naujų keramikos konservavimo metodų kūrimas // Chemija ir cheminė technologija : studentų mokslinės konferencijos pranešimų medžiaga. Klaipėda, 2012, gegužės 15 d. Klaipėda : Klaipėdos universiteto leidykla, 2012, p. 148-150.

O. Darčanova, T. Sabirovas, A. Beganskienė, A. Kareiva. Rašalo pažeisto popieriaus naujų stabilizuojančių medžiagų tyrimas // Chemija ir cheminė technologija : studentų mokslinės konferencijos pranešimų medžiaga. Klaipėda, 2012, gegužės 15 d. Klaipėda : Klaipėdos universiteto leidykla, 2012, p. 52-54.

M. Misevičius, J. Jorgensen, A. Kareiva. Synthesis and structural characterization of Sr4Al14O25 with partial substitution of Sr2+ by Ca2+ and Ba2+ // Chemistry and chemical technology of inorganic materials : proceedings of scientific conferenceChemistry and chemical technology. Kaunas : Technologija, 2012, p. 5-9.

J. Pilipavičius, D. Sakalauskas, N. Rusteika, A. Kaušas, A. Beganskienė, A. Kareiva. Synthesis of carbon nanotube composite coatings for ultrafast mode-locking // Chemistry and chemical technology of inorganic materials : proceedings of scientific conferenceChemistry and chemical technology. Kaunas : Technologija, 2012, p. 120-126.

M. Misevičius, A. Kareiva. Stroncio aliuminato Sr4Al14O25, dalinai pakeisto Ba ir Ca vietoje Sr, sintezė ir tyrimas // Chemija ir cheminė technologija : studentų mokslinės konferencijos pranešimų medžiaga. Klaipėda, 2012, gegužės 15 d. Klaipėda : Klaipėdos universiteto leidykla, 2012, p. 133-136.

S. Žeimytė, A. Žalga. Thermoanalytical study of the lanthanum molybdate nitrate-tartrate procursirs prepared by aqueouse sol-gel synthesis route // Chemistry and chemical technology of inorganic materials : proceedings of scientific conferenceChemistry and chemical technology. Kaunas : Technologija, 2012, p. 15-20.

R. Trusovas, K. Ratautas, G. Račiukaitis, J. Barkauskas, I. Stankevičienė, R. Mažeikienė. Formation of graphene domains in graphite oxide by picosecond laser treatment // Radiation interaction with material and its use in technologies 2012 : 4rd international conference, Kaunas, Lithuania, May 14-17, 2012 : program and materials. Kaunas : Technologija, 2012, p. 452-454.

COOPERATION

Department of Inorganic Chemistry, Masaryk University, Brno (Czech Republic)
Department of Analytical and Inorganic Chemistry, Tallinn University of Technology (Estonia)
Department of Inorganic Chemistry, University of Tubingen (Germany)
Department of Inorganic Chemistry, Charles University of Prague (Czech Republic)
Department of Environmental and Analytical Chemistry, Vilnius University (Lithuania)
Department of Chemistry, Aarhus University (Denmark)
Department of Chemistry, University of Applied Sciences, Muenster (Germany)
Paul Scherrer Institut, FEMTO-SLS, Villigen (Switzerland)
Center for Physical Sciences and Technology, Vilnius (Lithuania)
Gdansk University of Technology, Dept. of Chemical Technology, Gdansk (Poland)
Norwegian University of Science and Technology (NTNU) (Norway)
Norwegian University of Life Sciences (UMB) (Norway)
National Taipei University of Technology (Taipei Tech) (Taiwan, R.O.C.)
Riga Technical University, Riga (Latvia)
University of Latvia, Riga (Latvia)
Institute of Biochemistry, Vilnius (Lithuania)
Department of Civil and Environmental Engineering, Pennsylvania State University (USA)
DHI Water & Environment, Copenhagen (Denmark)
Instituto di Cristallogtapfia, Consiglo Nazionale delle Ricerche, Rome (Italy)
Solid State Physics Group, Experimental Physics Department, University of Torino (Italy)
Laboratoire des Materiaux et Genie Physique (Lmgp) – ENSPG, INPG, Grenoble, Umr5628 - CNRS (France)
Instituto de Ciencia de Materiales de Barcelona, Consejo Superior de Investigaciones Cientificas, Barcelona (Spain)
Slovak Academy of Sciences, Institute of Electrical Engineering, Bratislava (Slovakia)
IMEC, Silicon Process & Device Technology Division, Leuven (Belgium)
Centre d’Investigació en Nanociència i Nanotecnologia (CIN2), Bellaterra (Spain)
SAFC Hitech Enabling Technology (United Kingdom)
Semiconductor Physics Institute, Vilnius (Lithuania)
IHP GmbH, Frankfurt am Oder (Germany)
University Henri Poincare, Institut Jean Lamour, Vandœuvre-lès-Nancy, France
ST Microelectronics S.R.L., Agrate Brianza, Milan (Italy)
Instituto de Óptica, Consejo Superior De Investigaciones Cientificas, Madrid (Spain)
University of Technology Dresden, Semiconductor and Microsystems Technology Laboratory, Dresden (Germany)
Ruhr-University Bochum, Dept. Inorganic Materials Chemistry, Bochum (Germany)
AQUAporin, Copenhagen (Denmark)
University of Southern Denmark, MEMPHYS Centre for Biomembrane Physics, Odense (Denmark)
Lund University, Department of Plant Biochemistry, Lund (Sweden)
Málaga University, Department of Applied Physics I, Malaga (Spain)
Veolia Water – Anjou Recherche, Anjou (France)
Technical University of Denmark, the Membrane Group, Copenhagen (Denmark)
Telemark University College, Porsgrunn (Norway)
Consiglio Nazionale Delle Ricerche, Rome (Italy)
INFM Laboratorio MDM, Milan (Italy) (CNR)
Institute of Sorption and Problems of Endoecology, Kyiv (Ukraine)
EMT Research ASA, Porsgrunn, (Norway)

OTHER SCIENTIFIC ACTIVITIES

Prof. A. Kareiva –

member of the Lithuanian Academy of Sciences;
editorial board member of the journal Chemine Technologija (Chemical Technology);
deputy editor of the journal Chemija (Chemistry);
member of the Council of Alytus College;
chairman of Chemistry Section of the Lithuanian Academy of Sciences;
deputy Chairman of the Department of Mathematics, Physics and Chemistry of the Lithuanian Academy of Sciences;
member of Evaluation Board of Institute of Thermal Insulation of Vilnius Gediminas Technical University;
member of Scientific Council of Centre for Physical Sciences and Technology;
the Honorary International Chair Professor at the National Taipei University of Technology, Taiwan (2012–2014).

Prof. A. Abrutis –

expert of the Research Council of Lithuania.

DEPARTMENT OF PHYSICAL CHEMISTRY

24 Naugarduko, LT-03225 Vilnius
Tel. 233 6419, 213 1572, fax 233 0987
E-mail:

Head – Prof. Habil. Dr. Arūnas Ramanavičius

STAFF

Professors: Dr. H. Cesiulis, Habil. Dr. A. Malinauskas (part-time), Habil. Dr. R. Ramanauskas (part-time), Habil. Dr. A. Ramanavičius.
Docents: Dr. D. Plaušinaitis, Dr. A. Valiūnienė, Dr. R. Valiūnas (part-time).
Lecturers: Dr. Ž. Margarian, Dr. S. Šakirzanovas.
Research fellows: Dr. D. Plaušinaitis (part-time), Habil. Dr. A. Ramanavičius (part-time).
Doctoral students: T. Maliar, S. Kozlovskaja, B. Rakovska.

RESEARCH INTERESTS

Electrochemical processes at the interface solid electrode / liquid electrolyte

RESEARCH PROJECTS CARRIED OUT IN 2012

Projects Supported by University Budget

Development of Electroanalytical Systems. Prof. A. Ramanavičius. 2011–2015.

Investigation of the Interfacial Processes. Prof. H. Cesiulis. 2011–2015.

New sensing platform based on modified glassy carbon (GC) suitable for design of heavy metal-ion sensor is reported in this study. GC-based electrodes were electrochemically modified by poly-5-nitro-1,10-phenanthroline (poly-5NP) and poly-5-amino, 6-nitro-1,10-phenanthroline (poly-5A6NP) layers. Grafting of electrochemically formed poly-5NP and poly-5A6NP layers at the GC electrode surface was confirmed by electrochemical reduction of nitro groups into amine groups. Presence of grafted poly- 5NP and poly-5A6NP layers and formation of their reduced forms on the GC electrode surface were verified by cyclic voltammetry, electrochemical impedance spectroscopy, contact angle measurements, ellipsometry and X-ray photoelectron spectroscopy. The applicability of poly-5NP- and poly-5A6NPfunctionalized carbon surfaces for the determination of Cu(II) ions was demonstrated by formation of complexes between GC-grafted poly-5NP and poly-5A6NP layers and Cu(II) ions.
The obtained oxide films are continuous, amorphous, and the smoothest surface is obtained after Ti anodizing in 2 M H3PO4+0.05 M NH4F solution. At concentration of NH4F 0.2M, the nanotubes of TiO2 are formed at the temperatures 10-20°C and AP=20V. The length of nanotubes determined by FIB technique is in the range 650-730 nm, and the diameter of pores is 60-80 nm. The photocurrents and photopotentials correlate with fluorine incorporation into film, and the values of ones were obtained for films not included fluorine, i.e. for films obtained in pure 2M H3PO4. The anodic photovoltage up to 2 V (at constant current 1 mA/cm2) and photocurrent up to 5 mA/cm2 (at constant anodic potential 1.8 V) have been detected in 0.05M NaOH solution.
Nanocrystalline Co-W coatings with 13–36 at.% W were obtained from citrate-borate electrolyte under DC and PC plating conditions. A crystalline structure is obtained when the tungsten content is in the range of 13 to 20.8 at.% W. In this case coatings present a mixture of two crystalline phases: W solid solution in hcp Co and a small quantity of Co with fcc structure. When the quantity of W exceeds 21–22 at.% the lattice constants of hcp Co gain values characteristic for those of Co3W. The influence of annealing temperature on the structure of Co-W alloys having 24.5 at.%% and 34.4 at.% has been investigated. In coatings containing 24.5 at.% W, a well developed polycrystalline structure of Co3W appears at 400 °C with {200}, {201} and {220} textures. On the contrary, Co-W coatings with a high tungsten content of 34.4 at.% W maintain their grain size at 400 °C, and a recrystallization into a polycrystalline Co3W structure occurs above 600 °C. At 800 °C, a dominating {201} texture develops. The polycrystalline structure remains stable on further heating up to 1000 °C. The grain size increases during heating from 3-5 nm up to 47–53 nm.
The properties of thiol self-assembled monolayer HC18 (SAM) formed on gold substrate are researched. Long term stability of surface properties in ethanol and water is evaluated. With a goal of finding a method for removal of SAMs without altering of surface structure and morphology electrochemical oxidation in acidic solution (0.1 M H2SO4) and electrochemical reduction in basic solution (0.5 M NaOH) is performed using cyclic voltammetry. In addition properties are researched using Electrochemical Impedance Spectroscopy and Quartz Crystal Micro Balance. It was determined that long term exposure to ethanol reversibly desorbs one third of initial SAM molecules. If specimen is again immersed in thiol solution its properties return to initial state. In addition it was determined that when SAM is exposed to water SAM structure is penetrated by water molecules to an extensive degree. Properties of surface can be significantly altered by this effect. Another point made in this work is that thiol can be removed using electrochemical oxidation. For an effective removal the procedures duration must be over 3 hours, however. During electrochemical reduction desorbed SAM molecules do not leave surface region, thus, once the experiment is finished they adsorb back on the surface. Furthermore, during degradation of SAM its covered area does not change only layer’s average thickness. This effect is observed provided that there are enough thiol molecules to cover the area.

MAIN PUBLICATIONS

Articles

S. Kozlovskaja, R. Garjonytė, A. Malinauskas. Amperometric responses of some biosensor-related analytes at electrodes coated with semipermeable polymer layers: a comparative study // Chemija / Lietuvos mokslų akademija. Vilnius : Lietuvos mokslų akademijos leidykla. 2012, t. 23, nr. 1, p. 7-11.

L. Leonavičienė, G. Kirdaitė, R. Bradūnaitė, D. Vaitkienė, A. Vasiliauskas, D. Zabulyte, A. Ramanavičienė, A. Ramanavičius, T. Ašmenavičius, Z. Mackiewicz. Effect of gold nanoparticles in the treatment of established collagen arthritis in rats // Medicina. Kaunas : Kauno medicinos universitetas. 2012, t. 48, nr. 2, p. 91-101.

T. Maliar, J. Boženko, H. Cesiulis, I. Prosyčevas. Electrochemical Aspects of the Synthesis of Iron Particles // Materials science = Medžiagotyra / Kaunas University of Technology, Academy of Sciences of Lithuania. Kaunas : Technologija. 2012, vol. 18, no. 3, p. 223-227.

T. Maliar, J. Boženko, H. Cesiulis, I. Prosyčevas. Electrochemical aspects of the synthesis of iron particles // Materials science = Medžiagotyra / Kaunas University of Technology, Academy of Sciences of Lithuania. Kaunas : Technologija. 2012, vol. 18, no. 3, p. 223-227.

Y. Oztekin, Z. Yazicigil, A. Solak, Z. Ustundag, Z. Kilic, S. Bilge. Surface modification and characterization of phenanthroline nanofilms on carbon substrate // Surface and Interface Analysis. Bognor Regis : John Wiley & Sons Ltd. 2011, Vol. 43, iss. 5, p. 923-930.

N. Tsyntsaru, H. Cesiulis, A. Budreika, X. Ye, R. Juškėnas, J. Celis. The effect of electrodeposition conditions and post-annealing on nanostructure of Co-W coatings // Surface and coatings technology. Lausanne : Elsevier Science. 2012, vol. 206, no. 19-20, p. 4262-4269.

N. Tsyntsaru, S. Belevsky, H. Cesiulis, A. Dikusar, J. Celis. Cu/Co-W nanolayers electrodeposited from single bath and investigations of their nanohardness // Surface Engineering and Applied Electrochemistry. Heidelberg : Allerton Press, Inc. distributed exclusively by Springer Science+Business Media LLC. 2012, vol. 48, no. 5, p. 418-425.

N. Tsyntsaru, H. Cesiulis, M. Donten, J. Sort, E. Pellicer, E. Podlaha-Murphy. Modern trends in tungsten alloys electrodeposition with iron group metals // Surface Engineering and Applied Electrochemistry. Heidelberg : Allerton Press, Inc. distributed exclusively by Springer Science+Business Media LLC. 2012, vol. 48, no. 6, p. 225-231.

COOPERATION

Institute of Chemistry (Lithuania)
University of Kiel (Germany)
Colorado State University (USA)
Warsaw University (Poland)
Katholieke Universiteit Leuven (Belgium)
Ecole Centrale Paris (France)
Northeastern University, Boston (USA)
Institute for Applied Physics NAS Moldova (Moldova)

DEPARTMENT OF ORGANIC CHEMISTRY

24 Naugarduko, LT-03225 Vilnius
Tel. 219 3197, fax 233 0987
E-mail:

Head – Prof. Habil. Dr. Sigitas Tumkevičius

STAFF

Professors: Habil. Dr. E. Butkus (part-time), Habil. Dr. S. Tumkevičius, Habil. Dr. P. Vainilavičius.
Docents: Dr. A. Brukštus, Dr. M. M. Burbulienė, Dr. I. Čikotienė, Dr. V. Jakubkienė, Dr. V. Masevičius, Dr. S. Stončius (part-time), Dr. R. Vaitkus (part-time), Dr. A. Žilinskas.
Lecturers: Dr. J. Dodonova (part-time), Dr. L. Riauba (part-time).
Assistent: J. Dodonova (part-time).
Research fellows: Habil. Dr. E. Butkus (part-time), Dr. M. M. Burbulienė (part-time), Dr. V. Jakubkienė (part-time), dr. S. Stončius (part-time).
Doctoral students: G. Bagdžiūnas, A. Bilinska, J. Bucevičius, R. Bukšnaitienė, E. Čapkauskaitė, J. Dodonova, R. Juškėnas, I. Karpavičienė, G. Petraitytė, D. Račkauskaitė, S. Višniakova.

RESEARCH INTERESTS

Enantioselective synthesis of polycyclic molecules
Organocatalysts for asymmetric synthesis
Metal-catalyzed organic reactions
Self-assembly of organic molecules
Heterocyclic chemistry
Synthesis of supramolecular structures based on chiral bicyclic frameworks fused with heteroaromatic fragments
Design, synthesis and transformations of novel nitrogen, oxygen and/or sulphur heterocycles, their functional derivatives and structural analogs of natural compounds
Chiroptical properties
Light-emitting organic materials
Charge-transporting organic materials
Biological activity of organic compounds
Crystal engineering
X-ray diffraction
NMR, FTIR, Raman, UV, CD spectroscopy of organic compounds
Quantum chemical methods

RESEARCH PROJECTS CARRIED OUT IN 2012

Projects Supported by University Budget

Design and Synthesis of New Organic Materials, Investigation of their Properties and Self-Assembling, Application in Optoelectronics and Biochemistry. Prof. E. Butkus, Prof. S. Tumkevičius. 2009–2013.

Highly regioselective oxygen transfer from nitro groups to carbon-carbon triple bonds has been achieved by employment of iodine monochloride or molecular iodine. The precursors are heterocyclic or aromatic compounds, each bearing a nitro group ortho to an internal alkyne. The developed methodology is general for the preparation of a wide range of fused isoxazoles. A three-component reaction among 2-alkynylquinoline-3-carbaldehydes, primary amines, and C- or P-pronucleophiles leading to novel 1,2-dihydrobenzo[b][1,6]naphthyridines was developed using microwave initiation in an absence of any catalysts. A facile, economic, and efficient protocol for the reduction of nonconjugated Δ2-isoxazolines to the corresponding β-hydroxy ketones using Al/CuCl2 as the reducing agent has been developed. Novel 4,6-diamino- and 2-aminopyrimidines from the corresponding chloro derivatives via N-nitrosoamine intermediates were synthesized.
Cyclization reactions of pyrimidine derivatives to form furo-, pyrrolo- and pyrazolopyrimidines were studied. Investigation of the reactions of the obtained heterocycles with bifunctionalized reagents led to the development of a simple and efficient synthesis of novel ortho- and peri-annulated heterocyclic systems—2,6,7,9-tetrahydro-8H-pyrazolo[5,4,3-de]pyrimido[4,5-e][1,4]diazepine, 2,6,7,9-tetrahydro-8H-pyrazolo[5,4,3-de]pyrimido[5,4-f][1,4]thiazepine, and 6,9-dihydro-2H-pyrazolo[3,4,5-ef]pyrimido[5,4-f][1,2,4]triazepine. Mitsunobu reaction of (furo[2,3-d]pyrimidin-5-yl)methanol with N-mesyl- or N-nosylarylamines was investigated. Some arylpyrimidines were found to exhibit strong blue fluorescence. Synthesis of fused nitrogen heterocycles containing the bicyclo[3.3.1]nonane framework has been accomplished. Synthesis of organic tertiary amonium salts was carried out and their effect on obsolescence and disintegration processes of paper (cellulose) has been studied. Enzymes of vegetables of the family Apiaceae were found to be promising catalysts for the enantioselective reduction of bicyclo[3.3.1]nonane-2,6-dione.
The syntheses and crystal structures of unsaturated bicyclo[3.3.1]nonane derivatives containing various functionalities were performed and their intermolecular interactions examined. The unsaturation and hydrogen bonds in the bicyclononane diene diol, in the dienone, the bromo and nitrile derivatives were found significant for the overall crystal structure and intermolecular networks. The two bromine atoms have significant halogen–halogen interactions. In several structures 2D nets can be identified and overall structures can be interpreted as close packing of these layers. A synthesis of diastereomeric bicyclic dibenzoyl esters derived from enantiomerically pure (1S,5S)-bicyclo[3.3.1]nonane-2,6-dione was accomplished. Chiroptical properties were studied and diastereomeric esters exhibited exciton couplets in the circular dichroism spectra because of transannular interaction between non-conjugated benzoate chromophores. Theoretical computation of the CD spectra of diastereomers correctly reproduced the sign of the exciton couplets in the studied molecules. The enantiomer resolution of N-protected 9-azabicyclo[3.3.1]nonane-2,6-diols was achieved by crystallization of their diastereomeric esters derived from (1S)-(−)-camphanic chloride. The enantiomers of N-Boc protected diol were converted into the corresponding enantiomerically pure diones, the absolute configuration of which was inferred from the TDDFT calculations of the electronic circular dichroism spectra (ECD) and was confirmed via analysis of the CD spectra of the diol dibenzoates and application of the benzoate exciton chirality method.

Projects, Programmes, Issues Supported by the Research Council of Lithuania

Synthesis of Chiral Synthons and Application in Supramolecular Chemistry and Organocatalysis. Dr. S. Stončius. 2011–2015.

An Integrated Discovery of Novel Anti-Cancer Compounds: From Fundamental Researches to Purposeful Modeling and Synthesis. Global Grant Project Nr. VP1-3.1-ŠMM-07-K-01-002. Doc. I. Čikotienė. 2011–2015.

International Science Programmes and Projects

Nordic-Baltic Network Excellent Nordic Chemistry. Funded by the Nordic Research Council (Nordforsk). 2009–2012.

MAIN PUBLICATIONS

Articles

A. Bilinska, A. Žilinskas. Synthesis of chiral bicyclo[3.3.1]nonane derivative as ionic liquid and using it for asymmetric Michael's addition reaction // Chemija / Lietuvos mokslų akademija. Vilnius : Lietuvos mokslų akademijos leidykla. 2012, t. 23, nr. 4, p. 301-305.

S. Tumkevičius, A. Voitechovičius, P. Adomėnas. Synthesis of novel 2,4,6-triarylpyrimidines // Chemija / Lietuvos mokslų akademija. Vilnius : Lietuvos mokslų akademijos leidykla. 2012, t. 23, nr. 1, p. 61-67.

R. Bukšnaitienė, I. Čikotienė. A facile and efficient synthesis of 1-trichloromethyl-1,2-dihydrobenzo[b][1,6]naphthyridines via three-component reaction among 2-alkynylquinoline-3-carbaldehydes, primary amines, and chloroform // Heterocyclic Communications. Berlin : Walter de Gruyter GmbH & Co. KG. 2012, Vol. 18, no. 2, p. 87-92.

N. Cabrera-Benitez, E. Perez-Roth, M. Casula, A. Ramos-Nuez, C. Rios-Luci, C. Rodriguez-Gallego, I. Sologuren, V. Jakubkienė, A. Slutsky, J. Padron, J. Villar. Anti-Inflammatory Activity of a Novel Family of Aryl Ureas Compounds in an Endotoxin-Induced Airway Epithelial Cell Injury Model // PLoS ONE [Elektroninis išteklius]. San Francisko : Public Library of Science. 2012, Vol. 7, iss. 11, p. e48468.

S. Sharp, S. Roe, E. Kazlauskas, I. Čikotienė, P. Workman, D. Matulis, C. Prodromou. Co-Crystalization and In Vitro Biological Characterization of 5-Aryl-4-(5-Substituted-2-4-Dihydroxyphenyl)-1,2,3-Thiadiazole Hsp90 Inhibitors // PLoS ONE [Elektroninis išteklius]. San Francisko : Public Library of Science. 2012, Vol. 7, iss. 9, p. e44642 (8 p.).

E. Čapkauskaitė, A. Zubrienė, L. Baranauskienė, G. Tamulaitienė, E. Manakova, V. Kairys, S. Gražulis, S. Tumkevičius, D. Matulis. Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases // European Journal of Medicinal Chemistry. Paris : Elsevier Masson. 2012, Vol. 51, p. 259-270.

V. Jakubkienė, I. Čikotienė. Effect of substituent structure on pyrimidine electrophilic substitution: a rebuttal // Tetrahedron. Oxford : Pergamon. 2012, vol. 68, iss. 10, p. 2294-2298.

S. Tumkevičius, J. Dodonova. Functionalization of pyrrolo[2,3-d]pyrimidine by palladium-catalyzed cross-coupling reactions (review) // Chemistry of Heterocyclic Compounds. New York : Springer. 2012, Vol. 48, no. 2, p. 258-279.

R. Vaitkus, G. Grincienė, E. Norkus. Inhibition of cyclodextrin acid hydrolysis by some inclusion complexes // Journal of inclusion phenomena and macrocyclic chemistry. Dordrecht : Springer Netherlands. 2011, vol 69, no 3-4, p. 345-347.

I. Čikotienė. Intramolecular Iodine-Mediated Oxygen Transfer from Nitro Groups to C=C Bonds // European journal of organic chemistry. Weinheim : Wiley - VCH Verlag GmbH & Co. KGaA. 2012, iss. 14, p. 2766-2773.

R. Vaitkus, S. Sjoberg. Large inclusion constants of Ī²-cyclodextrin with carborane derivatives // Journal of inclusion phenomena and macrocyclic chemistry. Dordrecht : Springer Netherlands. 2011, vol 69, no 3-4, p. 393-395.

I. Karpavičienė, R. Lapinskaitė, A. Brukštus, I. Čikotienė. Reductive Ring Cleavage of Nonconjugated Ī”2-Isoxazolines to Ī²-Hydroxy Ke-tones with Aluminum and Copper (II) Chloride // Synlett. Stuttgart : Georg Thieme Verlag. 2012, Vol. 23, p. 381-384.

V. Jakubkienė, V. Cėpla, M. Burbulienė, P. Vainilavičius. Synthesis and functionalization of 8-methyl-2h-pyrimido [2,1-c][1,2,4]triazine-3,6(1h,4h)-dione // Journal of heterocyclic chemistry. Hoboken : Wiley-Blackwell Publishing. 2012, vol. 49, iss. 4, p. 737-741.

G. Bagdžiūnas, E. Butkus, S. Stončius. Synthesis of diastereomeric bicyclo[3.3.1]nonane dibenzoyl esters and study of their chiroptical properties // Chirality. 2012, vol. 24, iss. 10, p. 810-816.

M. Burbulienė, A. Šimkus, P. Vainilavičius. Synthesis of new pyrimidinylthio-substituted 1,3,4-oxa(thia)diazoles and 1,2,4-triazoles // Journal of sulfur chemistry. Colchester : Taylor & Francis Ltd. p. 403-411.

V. Masevičius, R. Juškėnas, S. Tumkevičius. Synthesis of novel pyrazolo[3,4-d]pyrimidines peri-fused with 1,4-diazepine, 1,4-thiazepine, and 1,2,4-triazepine rings // Journal of heterocyclic chemistry. Hoboken : Wiley-Blackwell Publishing. 2012, Vol. 49, iss. 2, p. 315-320.

L. Labanauskas, V. Dudutienė, G. Urbelis, J. Šarlauskas, J. Sūdžius, D. Matulis, R. Striela, A. Žilinskas. Synthesis of substituted 2Ī»4Ī´2-[1,2,3]thiadiazolo[3,4-c]benzimidazoles and 2Ī»4Ī´2-[1,2,3,5]thiatriazolo[3,4-c]benzimidazoles // ARKIVOC : Archive for Organic Chemistry. Gainesville : ARKAT USA, Inc. 2012, part. 8, p. 17-26.

S. Višniakova, A. Žilinskas, S. Tumkevičius. Synthesis of 1,10-phenanthrolines fused with bicyclo[3.3.0]octane and bicyclo[3.3.1]nonane frameworks // Chemistry of Heterocyclic Compounds. New York : Springer. 2012, Vol. 48, no. 6, p. 943-949.

J. Dodonova, L. Skardžiūtė, K. Kazlauskas, S. Juršėnas, S. Tumkevičius. Synthesis of 4-aryl-, 2,4-diaryl- and 2,4,7-triarylpyrrolo[2,3-d]pyrimidines by a combination of the Suzuki cross-coupling and N-arylation reactions // Tetrahedron. Oxford : Pergamon. 2012, vol. 68, iss. 1, p. 329-339.

I. Čikotienė, R. Bukšnaitienė. Study on the reactions of acetylenic aldehydes with dimethyl phosphite in basic media: phosphonate-phosphate rearrangement versus 5-exo-dig cyclization reactions // Advanced synthesis and catalysis. Weinheim : Wiley - V C H Verlag GmbH & Co. KGaA. 2012, vol. 354, no 14-15, p. 2719-2726.

V. Masevičius, G. Petraitytė, S. Tumkevičius. 4-Amino-5-(arylaminomethyl)-2-(methylthio)furo[2,3-d]pyrimidines via Mitsunobu Reaction of 4-Amino-5-(hydroxymethyl)-2-(methylthio)furo[2,3-d]pyrimidine with N-Mesyl- and N-Nosylarylamines // Synthesis. Stuttgart : Georg Thieme Verlag. 2012, Vol. 44, iss. 9, p. 1329-1338.

E. Čapkauskaitė, S. Tumkevičius, D. Matulis. Synthesis of benzenesulfonamides containing azaheterocyclic moieties // Latvian Journal of Chemistry. Salaspils : Institute of Inorganic Chemistry of the Riga Technical University. 2012, no. 1 : Materials of the Paul Walden 7th Symposium on organic chemistry (Riga, September 12-13, 2011), p. 54.

A. Voitechovičius, K. Karpavičius, A. Voitechovičiūtė, S. Tumkevičius, P. Adomėnas. Synthesis of novel 4,6-diaryl- and 4,6-bis(2-arylvinyl)-pyrimidines // Latvian Journal of Chemistry. Salaspils : Institute of Inorganic Chemistry of the Riga Technical University. 2012, no. 1 : Materials of the Paul Walden 7th Symposium on organic chemistry (Riga, September 12-13, 2011), p. 77.

Materials of conferences

I. Čikotienė. Iodine-mediated intramolecular oxygen transfer from nitrogroups to Cā=C bonds // 25th European colloquium on heterocyclic chemistry, August 13-17, 2012, United Kingdom. Reading : University of Reading, 2012, p. PO 19.

M. Burbulienė, L. Rekovič, P. Vainilavičius. N(3)-acilmetil-4-chinazolinonų reakcijos su sierinimo reagentais tyrimas // Organinė chemija = Organic chemistry : mokslinės konferencijos pranešimų medžiaga. Kaunas : Technologija, 2012, p. 14.

M. Burbulienė, O. Bobrovas, P. Vainilavičius. 1-amino-1,2,3,5-tetrahidroimidazo[2,1-a]chinazolin-2,5-diono oksidacijos reakcijos tyrimas // Organinė chemija = Organic chemistry : mokslinės konferencijos pranešimų medžiaga. Kaunas : Technologija, 2012, p. 51.

R. Urbonas, S. Tumkevičius. 2,4,7-Triaril-7H-pirolo[2,3-dpirimidinų sintezė, panaudojant Pd(0), Ni(0) ir Cu(I) katalizuojamas reakcijas // Chemija ir cheminė technologija : studentų mokslinės konferencijos pranešimų medžiaga. Klaipėda, 2012, gegužės 15 d. Klaipėda : Klaipėdos universiteto leidykla, 2012, p. 214-216.

Patents

D. Matulis, I. Čikotienė, E. Kazlauskas, J. Matulienė. 5-aryl-4-(5-substituted 2,4-dihydroxyphenyl)-1,2,3-thiadiazoles as inhibitors of HSP90 chaperone and the intermediates for production thereof // 20120201.

D. Matulis, I. Čikotienė, E. Kazlauskas, J. Matulienė. 5-aryl-4-(5-substituted 2,4-dihydroxyphenyl)-1,2,3-thiadiazoles as inhibitors of Hsp90 chaperone and the intermediates for production thereof : patent no.: US 8,314,132 B2 / inventors: Matulis; Daumantas (Vilnius, LT), Cikotiene; Inga (Vilnius, LT), Kazlauskas; Egidijus (Vilnius, LT), Matuliene; Jurgita (Vilnius, LT) // 20121120.

COOPERATION

Orleans University (France)
Latvian Institute of Organic Synthesis (Latvia)
Lund University (Sweden)
La Laguna University (Spain)
Indiana University, Indianopolis (USA)
Jyvaskyla University (Finland)
University of Madeira (Portugal)
University of Southern California, Los Angeles (USA)
Institute of Biochemistry (Lithuania)
Institute of Biotechnology (Lithuania)
Institute of Chemistry (Lithuania)
Institute of Cardiology of Kaunas University of Medicine (Lithuania)
Institute of Physics (Lithuania)

OTHER SCIENTIFIC ACTIVITIES

Prof. E. Butkus –

organic chemistry section editor of the international journal Central European Journal of Chemistry http://chemistry.cesj.com;
editorial board member of the journal Chemija (Chemistry);
member of the EU program committee of the FP7 Ideas program;
member of the Lithuanian Academy of Sciences;
member of the organising committee of the international conference onorganic synthesis Balticum Organicum Syntheticum 2012.

Prof. S. Tumkevičius –

editorial board member of the journal Chemija (Chemistry);
editorial board member of the international journal Chemistry of Heterocyclic Compounds;
member of the organising committee of students’ conference Chemistry and Chemical Technology.

DEPARTMENT OF POLYMER CHEMISTRY

24 Naugarduko, LT-03225 Vilnius
Tel. 219 3227, fax 233 0987
E-mail:

Head – Prof. Dr. Ričardas Makuška

STAFF

Professors: Dr. R. Makuška, Dr. S. Budrienė.
Docents: Dr. E. Udrėnaitė, Dr. A. Vareikis.
Lecturer: Dr. T. Kochanė.
Research fellows: Dr. V.Pamedytytė, A.Strakšys.
Doctoral students: Č.Višnevskij, A. Burvytė, J. Jonikaitė-Švėgždienė, G. Čiuta.

RESEARCH INTERESTS

Controlled radical polymerization of ionogenic monomers and macromonomers
Synthesis and properties of polymeric charge-containing molecular brushes
Polyelectrolytes from natural and synthetic building blocks
Chitosan modification and properties of chitosan derivatives
Interaction of cationic polymers with dna, gene transfection
Polymeric bead-form carriers for immobilization of enzymes
Immobilization of beta-galactosidase, alkaline phosphatase, pullulanase and maltogenase
Microencapsulation of various substances in polymeric beads

RESEARCH PROJECTS CARRIED OUT IN 2012

Projects Supported by University Budget

Synthesis and Study of Hydrophilic Polymers for Bio- and Nanotechnologies. Prof. R. Makuška,2011–2015.

New technique of ATRP including intermediate for supplemental activators and reducing agents was developed and tested under polymerization of cationic monomers. Newly proposed intermediate redox system contained iron or copper and oxidized ascorbic acid or iron (III) chloride. Cationic monomer METAC was polymerized by eATRP. Electrochemically mediated ATRP of METAC revealed relatively less control of polymerization under eATRP conditions compared to ARGET ATRP. Several types of multifunctional RAFT chain transfer agents were synthesized and used for the synthesis of multiblock copolymers. Complexation of chitosan and chlorophyllin was studied by turbidimetric measurements and DLS. It was determined that photoactivated chlorophyllin-deficient complex in slightly acidic environment was very efficient antibacterial material against Gram (-) bacteria. New type of poly(urethane urea) (PUU) microparticles based on of poly(vinyl alcohol) and 4,4’-methylenebis(cyclohexyl isocyanate) was synthesized. The effects of initial molar ratio of the components, reaction time and temperature on yield of PUU, quantity of functional groups, thermal properties, surface area and pore size distribution of microparticles were studied. PUU microparticles were used as carriers for immobilization of maltogenase.

Projects, Programmes, Issues Supported by Lithuanian State Science and Studies Foundation

Polymeric Anionic Bottle-Brush Structures as Mimics for Biolubricants. Project of the scientist group MIP-51/2012. Prof. R. Makuška. 2012–014.

Ordered Research Projects

Project ordered by Thermo Fisher Scientific (CC Fermentas), MTS-130000-2135. Prof. R. Makuška, 2012.

MAIN PUBLICATIONS

Articles

I. Buchovec, R. Kokštaitė, Ž. Lukšienė, V. Pamedytytė, R. Makuška. Antimicrobial efficiency of photoactivated chlorophyllin-chitosan complex // Cheminė technologija / Kauno technologijos universitetas. Kaunas : Technologija. 2012, nr. 3, p. 54-57.

A. Shovsky, I. Varga, R. Makuška, P. Claesson. Adsorption and Solution Properties of Bottle-Brush Polyelectrolyte Complexes: Effect of Molecular Weight and Stoichiometry // Langmuir. Washington : American Chemical Society. 2012, vol. 28, iss. 16, p. 6618-6631.

A. Tolstov, D. Gromadzki, M. Netopilik, R. Makuška. Aqueous AGET ATRP of sodium 2-acrylamido-2-methyl-N-propane sulfonate yielding strong anionic comb polyelectrolytes // e-Polymers. Strasbourg : European Polymer Federation. 2012, no 075, p. [1-12].

C. Uzum, R. Makuška, K. von. Effect of Molecular Architecture on the Polyelectrolyte Structuring under Confinement // Macromolecules. Washington : American Chemical Society. 2012, Vol. 45, iss. 7, p. 3168-3176.

X. Liu, A. Dedinaitė, M. Rutland, E. Thormann, Č. Višnevskij, R. Makuška, P. Claesson. Electrostatically anchored branched brush layers // Langmuir. Washington : American Chemical Society. 2012, vol. 28, iss. 44, p. 15537-15547.

COOPERATION

CC Fermentas, part of Thermo Fisher Scientific (Lithuania)
Royal Institute of Technology (Sweden)
Institute of Macromolecular Chemistry (Czech Republic)

OTHER SCIENTIFIC ACTIVITIES

Prof. R. Makuška –

expert of the Research Council of Lithuania;
member of the scientific committee of the international conference Baltic Polymer Symposium;
editorial board member of the journal Chemija (Chemistry).